Thesis (M.D.) - University of Birmingham, Dept of Obstretrics and Gynaecology, 1977.
Although protein-energy malnutrition (PEM) affects 50% of hospitalized patients, its effects on the hypothalamic-pituitary-gonadal (HPG) axis have not been extensively investigated. To investigate the effects of PEM on the HPG axis in hospitalized patients, 62 inpatients ages y (35 men and 27 women) had a nutritional and hormonal by: Interest is growing in the potential effect of gonadal hormones, prolactin, and the hypothalamic–pituitary–gonadal axis in schizophrenic psychoses. Many studies from clinical, epidemiological, and fundamental research have confirmed that oestradiol, the main component of oestrogens, can have protective effects in schizophrenic by: To mimic the human pathology of anovulation, we continuously infused female mice with prolactin. Our studies demonstrated that hyperprolactinemia in mice induced anovulation, reduced GnRH and. Hypothalamic-pituitary gonadal axis and immune response imbalance during chronic ﬁlarial infections amicroﬁlaremic women, whereas the prolactin concentration was higher in microﬁlaremics. The plasma concentrations of TNF-a, IFN-c, IL-1 and IL-6 were higher in microﬁlaremic women. Study subjects and methods.
Cross-sectional studies in Australia and the Philippines and a longitudinal prospective study in a selected Australian sample of breast-feeding mothers have shown that basal serum prolactin (PRL) concentrations are elevated during 15–21 months of lactational amenorrhoea. The hypothalamic-pituitary-gonadal axis (HPG axis) alludes to the connection between the hypothalamus, pituitary gland, and gonads. It is an important control mechanism mainly involved in the development and regulation of the reproductive system and . The age at puberty may be associated with health consequences later in adulthood. Normal function of the hypothalamic-pituitary-gonadal (HPG) axis is dependent on the meticulous spatio-temporal orchestration of gonadotropin-releasing hormone (GnRH) neuron development in the hypothalamus. ↑ Prolactin suppresses the hypothalamic pituitary gonadal axis resulting in ↓ GnRH and ↓ FSH/LH -Men often present with more advanced prolactin secreting tumors than women-this is also true of postmenopausal women AG Test 1 L2 Study Guide. 29 terms. hollyfire2 PLUS. A&P 2_CH 16 (Endocrine System) 46 terms.
Objectives: To investigate abnormalities of the hypothalamic-pituitary-gonadal (HPG) axis and cortisol concentrations in young women with primary fibromyalgia (FM); and to determine whether depression, fatigue, and sleep disturbance affect these hormones. Methods: Follicle stimulating hormone (FSH), luteinising hormone (LH), oestradiol, progesterone, prolactin, and cortisol concentrations in. Women from the study group had significantly higher levels of cortisol at each phase of the menstrual cycle than did the women from the control group (p prolactin levels on the third day of the cycle ( ± versus ± ng/dL; p. In addition to such epidemiological data, basic and translational studies have elucidated connections between gonadal steroids and neurotransmitters, neurotrophic factors and inflammation, the hypothalamic-pituitary-adrenal (HPA) axis, and systems of the brain related to emotional processing. 12,13 Together, the available research suggests that. DHEA-S levels were also found to be significantly lower in opioid-using women in multiple studies (12, 16, 23, 28), although this effect is not directly linked to the HPG axis but rather the hypothalamic-pituitary-adrenal axis because DHEA-S is the main androgen hormone in females coming from the adrenal gland and is under the regulation of ACTH.